Viruses and Their Replication - An Overview of Animal Virus Infection
6 important questions on Viruses and Their Replication - An Overview of Animal Virus Infection
What are the two differences between bacterial and animal viruses?
- The entire virion of animal viruses enters the host cell
- Eukaryotic cells contain a nucleus, where many animal viruses replicate
If an animal virus initially evades the immune system, animal viruses can catalyze at least four different outcomes. Give these outcomes.
- A virulent infection
- A latent infection
- A persistent infection
- Transformation
What is a latent infection?
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What is a persistent infection?
What enzyme do retroviruses use to transfer information from RNA to DNA?
Describe the replication of a retrovirus.
- Entry and uncoating of the retrovirus
- Activity of the reverse transcriptase (2 steps, 2 single standed RNAs into double stranded DNA)
- Viral DNA enters nucleus and integrates into host genome
- Transcription by host RNA polymerase forms viral mRNA and genome copies
- Translation of mRNA forms viral proteins; new nucleocapsids are assembled and released by budding
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