Post transcriptional gene control III - Gene-specific mRNA regulation
3 important questions on Post transcriptional gene control III - Gene-specific mRNA regulation
What is gene-specific mRNA regulation?
Ion transport and storage, reglation of the translational activity and degradation of mRNA in a gene-specific manner
Gene specific mRNA regulation: Ferritin
High iron: Ferritin needed
low iron: translation blocked, Ferritin reduces
low iron: translation blocked, Ferritin reduces
Gene specific mRNA regulation: Transferrin receptor (TFR)
High iron: TFR not needed, degraded mononucleotides
low iron: TFR needed, active IRE-BP (iron-responsive element binding protein) interfere with AU rich elements
low iron: TFR needed, active IRE-BP (iron-responsive element binding protein) interfere with AU rich elements
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