The Major Vertebrate Hormones - Protein and Peptide Hormones - Hypothalamic hormones
6 important questions on The Major Vertebrate Hormones - Protein and Peptide Hormones - Hypothalamic hormones
What is hypocretin (orexin)?
This hormone is found in the hypothalamus and projects to the rest of the brain and to the spinal cord. This hormone is involved in sleep, metabolic balance, and possibly activation of the sympathic nervous system.
Why are protein hormones extracted from the tissues of other animals anot used for clinical treatments in humans?
Because the proteins/peptides are slightly different in all mamalian species, the long term use may result in a immune response.
What are hypothalamic hormones?
Releasing and inhibiting peptides that act on a variety of cells in the anterior pituitary (act as neurotransmitters).
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Which six releasing hormones are found in the hypothalamus?
TRH- thyrotrophin-releasing hormone, somatocrinin/GHRH- growth hormone releasing hormone, GnRH - gonadaotropin releasing hormone, MRH - melanotropin releasing hormone, CRH- corticotropin releasing hormone (, and potentially kisspeptin).
Which inhibiting hormones are found in the hypothalamus?
Somatostatin/GHIH, Dopamine (DA)/PIH-prolactin inhibitory hormone + MIH-melanotropin inhibitory hormone, hypocretin.
What is/does dopamine (DA) do?
neurtotransmitter and monoamine, also serves as a neurohormone in the hypothalamus to inhibit the release of prolactin and melanotropin from the anterior pituitary.
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