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Summary: An Introduction To Medicinal Chemistry | 9780198749691 | Graham Patrick
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Read the summary and the most important questions on An Introduction to Medicinal Chemistry | 9780198749691 | Graham Patrick
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1 Drug an drug targets: an overview
This is a preview. There are 66 more flashcards available for chapter 1
Show more cards here -
What determines the dose level?
The dose level determines whether a drug acts as a medicine or as a poison. -
What is the therapeutic index?
The therapeutic index measures a drug's beneficial effects at a low dose versus its harmful effects at a higher dose. -
Wat voor lipiden zijn drug targets?
Celmembraanlipiden -
What indicates a high therapeutic index?
A high therapeutic index indicates a large safety margin between beneficial and toxic doses. -
What is selective toxicity?
Selective toxicity is the principle of drugs showing toxicity against foreign cells but not against normal host cells. -
Where act drugs?
Drugs acts on targets located on the cell membrane or within the cells themselves. -
What are drug targets?
Drug targets are macromolecules that have a binding site into which the drug fits and binds. -
How do drug normally bind?
Drugs typically bind to their target with intermolecular bonds. -
What interaction is between groups of opposide charges.
The interaction between groups of opposide charges is electrostatic or ionic. -
Between what are hydrogen bonds present?
Hydrogen bonds are formed between an electron-rich heteroatom and electron-deficient hydrogen.
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