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Actie - Preparation and Execution of Actions

5 important questions on Actie - Preparation and Execution of Actions

What is the role of subcorticol structures?

Preparation and execution of actions.

What are the two main types of corticol-subcorticol loop involved in the generation of movement?

The cerebrellar loop is involved in the coordination of movements. It may utilize a copy of the cortical motor commands to ensure that the desired movement occurs accurately and oocurs at the desired time.

The basal ganglia loop actually consists of around five different loops. Each loop had essentially the same architecture but projects to somewhat different structures in the basal ganglia and in the cortex. Of primary relevent here is the so-called motor circuit that passes through dorsal regions of the basal ganglia and projects to premotor areas and particularly strongly to the SMA.

What is the theory of Parkinson's disease?

Dopaminergic brain cells are lost in the pathways linking the substantia nigra and basal ganglia. Dopamine agonists therefore tend to be used in the treatment.

What is the theory of Huntington's disease?

A genetic disorder, which arises because of inhibitory neurons in the early part of the indirect pathway linking the basal ganglia with the thalamus.

What is the theory of Tourette's syndrome?

A correlation between tic severity and activation of the substantia nigra and cortical, striatal and thalamic regions in the direct pathway. The prefrontal cortex also tends to be more activate.