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Summary Biomolecules At Work

Course
- Biomolecules at work
- Pluk
- 2021 - 2022
- Radboud Universiteit Nijmegen
- Moleculaire Levenswetenschappen
162 Flashcards & Notes
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A snapshot of the summary - Biomolecules at work

  • 1 Lecture 1

  • 1.1 mitosis and meiosis

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  • Which one contributes to genetic variation, mitosis or meiosis?
    Meiosis
  • 1.2 single gene abnormalities

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  • What is X-linked recessive?
    1 mutant allele, son is affected, daughter is carrier
  • What is cytoplasmic inheritance?
    Progeny is the same phenotype as mother
  • 1.3 chromosomal abnormalities

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  • What is aberrant euploidy?
    Whole chromosome set is numerically mutated
  • 1.4 pedigree analysis

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  • Which mode of inheritance corresponds to the pedigree?
    X-linked dominant
  • 2 Lecture 2

  • 2.2 linkage analysis

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  • Are the genes in the picture in coupling, in repulsion or not linked at all?
    In repulsion
  • In what way can linked genes be separated form eachother to form recombinants?
    Crossovers
  • 2.3 linkage analysis trihybrid

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  • How can you deduce the genotypes of the original parents the heterozygous testcross parent?
    Use classes without crossovers to deduce heterozygous testcross parent. Form this deduce the original parent.
  • How can you determine the non-combinant and double crossover classes?
    Non-recombinant is the largest, double crossover is the smallest
  • 2.4 markers

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  • How is the variation at the marker locus called?
    Polymorphism

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