RNA sequencing - GL Mutational signatures in cancer (Ruben van Boxtel)
3 important questions on RNA sequencing - GL Mutational signatures in cancer (Ruben van Boxtel)
Mutational processes leave a characteristic footprint consisting of?
- Mutation type
- Direct sequence context
- Genomic distribution
How can a mutational process be identified?
By comparing to known signatures
The presence of a specific signature may be predictive for?
Treatment, predisposition, and cause of cancer
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