Lisinopril
3 important questions on Lisinopril
Why should Lisinopril not be taken in combination with salt substitutes?
Since Lisinopril inhibits the ACE system, potassium excretion is decreased. In combination with increased dietary intake of potassium via salt substitutes, this may lead to hyperkalaemia.
How should the Lisinopril dose be adjusted for patients with low glomerular filtration rate?
Lisinopril is excreted by the kidneys, so people who have slower excretion due to glomerular filtration impariment should have a lower dose to prevent overdosing.
Why could cough be a side-effect of drug treatment with Lisinopril?
Lisinopril may be responsible for accumulation of bradykinin, which is an inflammatory mediator that could cause cough.
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