Turning Blue - Respiratory disease - Chronic Bronchitis
6 important questions on Turning Blue - Respiratory disease - Chronic Bronchitis
What is the anatomic distribution of chronic bronchitis?
What factors lead to the excessive secretion of mucus in chronic bronchitis?
Other than hypersecretion of mucus, what else can be seen in chronic bronchitis?
Secondary infections may lead to acute exacerbations- although they are not a cause for chronic bronchitis, they may play a key role in maintaining the condition (cigarette smoke predisposes infection)
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What are the histological signs of chronic bronchitis?
Hyperplasia of the goblet cells
Metaplasia and dysplasia of the bronchial epithelium- due to the release of inflammatory mediators
Mucus plugging
Inflammation
Fibrosis
Hyperemia
Swelling
Oedema
What are the symptoms of chronic bronchitis?
No other respiratory dysfunction may be seen for years- overtime, hypercapnia, hypoxemia and cynosis may be seen.
What are the consequences of severe chronic bronchitis?
Superimposed acute infections may also cause death.
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