Lecture Six : Regulation of Animal Cell Shape
6 important questions on Lecture Six : Regulation of Animal Cell Shape
What are microtubules in the cytoskeleton ?
Functions :
- Maintain cell shape (resist compression)
- Motility (flagella and cilia)
- Transport of organelles and vesicles
What are Intermediate filaments in the cytoskeleton ?
- Super-coiled keratins (hair)
- Lamins (nucleus)
- Neurofilaments (neurons)
- Anchor organelles
- Maintain cell shape
What are the functions of the tight junction ?
- Tightly hold neighboring cells together
- Can form continuous seal
- Prevents movement of fluid across cell layers
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What are the functions of Desmosomes ?
- Cell anchor and linking of adjacent cells (connected by intermediate filaments)
What are the functions of Gap Junctions ?
- Rapid intracellular communication, through passage of ions/small molecules between cells
What is the composition and origin of the extracellular matrix (ECM) ?
- Different tissues require different types of ECM, since not all cells make direct contact with other cells.
- Cells secrete the materials that make up their ECM (by constitutive exocytosis)
- Proteoglycan matrix (trap water, resist compression)
- Membrane proteins (integrin, connect ECM to cytoskeleton, forms the communication link from outside of cell to inside)
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