Microbiology - Lecture Thirty : The Human Microbiome
3 important questions on Microbiology - Lecture Thirty : The Human Microbiome
What are the goals of the human microbiome project ?
A microbiome is the complete collection of microorganisms and their genes within a particular environment.
- To develop a reference set of microbial genome sequences and to perform preliminary characteristization of the human microbiome
- To explore the relationship between disease and changes in the human microbiome
- To develop new technologies and tools for computational analysis
- To establish a resource repository
- To study the ethical, legal and social implications of human microbiome research
What are some examples of the human gut microflora ?
Different species specialize in different parts of the body
- Bacterioidetes
- Actinobacteria
- Proteobacteria
- With High diversity and variety of species in each habitat
- Reflects how different sites are very different in conditions
- High density of microbes live in the GI tract
- Mostly in faeces, 50% of biomass is of bacteria
- The 4 main groups of gut microbiota:
- Bacterioidetes
- Actinobacteria
- Proteobacteria
How can our microbiome influence us ?
- All the microbes in us are competing with each other. If we have more good bacteria in us it is more difficult for bad bacteria to grow. THIS IS USEFUL.
- Fecal matter transplants from a healthy person can replace depleted good bacteria in a sick patient. These are used for recurrent Clostridium difficile infections.
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