Medicines by Design - n.m.r
5 important questions on Medicines by Design - n.m.r
What do the number of peaks tell you?
The number of chemical environments in which hydrogen nuclei are found.
What does the position of the absorption peaks (the chemical shift) tell you?
The type of proton
What does the amount fo splitting indicate?
The number of hydrogen atoms attached to the carbon atoms next to the one you are looking at
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What does the ratio of the number of equivalent hydrogen atoms tell you?
The area under the peak
Why is TMS used as a reference peak?
- its protons are highly shielded = its n.m.r peak is upfield of most other peaks
- it is non toxic + chemically inert
- it will not react with the sample material
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