Taste Sensations - Tingling sensations
2 important questions on Taste Sensations - Tingling sensations
In what do you find these compounds and what is there effect?
You find these compounds in Szechuan buttons (bloemetje) en ze hebben een tingeling effect. Same as in Sichuan Peppers
What factors are essential for making a tingling compound?
- Amide bond essential (free acids or esters do not work)
- 2,3-double bond essential
- Presence 6Z bond is crucial (all-trans compounds inactive)
- Above 2 factors should apply simultaneously
- Conjugated 2E,4E system might substitute 6Z
- Hydroxylation amino part not essential
- Alkyl chain length not essential, although a minimal chain length seems to be required (hexedienoyl-2E,4E (isobutylamide is inactive!)
- Terminal double bond not essential
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