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• 1 Lecture 1 - CH1

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• How can you get genetic improvement of an animal?

  - Artificial selection of the best animals
  - Natural selection

• How is an animal genetically improved with artificial selection of the best animals?

  - Increase in frequency of favourable alleles
  - Next generation is better than current generation

• 2 Lecture 2 - CH2

• How do you determine te traits in a breeding goal?

  Divide them in economic and non-economic

• What are other aspects to consider in a breeding goal?

  - Ethical aspects
  - Carbon footprint
  - Competitive position of breeding program

• 3 Lecture 3 - CH4

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• What is the aim of collecting information?

  - To be able to uniquely identify individuals
  - To get an accurate impression of the performance

• Why are semen and oocytes not preferred as source of DNA?

  Potentially large differences in DNA between cells due to meiosis

• What are genetic markers used for?

  - Parentage testing
  - Pedigree reconstruction
  - Estimate biodiversity
  - Estimate breeding value of animals
  - Find genes (and use for genetic testing)

• 5 Lecture 5 - CH7

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• What is a heritable disorder?

  - Often monegenic
  - Often recessive inheritance
  - Anything from little or no disomfort to lethal
  - In some cases occur in multiple species

• What if a recessive disorder is lethal?

  Prenatal mortalilty: no homozygous recessives born
  Occurs fairly often: early abortions, prolonged non-return interval

• What is the procedure for genome wide studies?

  1 Genotype many parents and their offspring
  2 For very many SNP markers, or even sequence info
  3 Look for absence of one of the homozygotes
  4 Test for deviation from H-W