Stem cells in cartilage and (re)generation (Abinzano)
3 important questions on Stem cells in cartilage and (re)generation (Abinzano)
Articular cartilage-resident chondroprogenitor cell (ACPC)
Recently identified multipotent cells that share important characteristics with stem cells. May be potential for cartilage regeneration.
How to recognize ACPCs?
- More IL-6 and PRG4 in comparison to MSC’s (mesenchymal stem cells) of the same donor
- Less extracellular matrix molecules compared to chondrocytes.
A problem with bioprinting tissue?
Cellular stress that arises by the pressure applied during the printing process, which can affect cells. Stem cells tend to recover better from this than other cells.
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