Molecular structure of DNA and RNA - Identification of DNA as the genetic material
14 important questions on Molecular structure of DNA and RNA - Identification of DNA as the genetic material
Which 4 criteria must the genetic material meet and what does it mean?
2. Transmission: the genetic material must be passed from parents to offspring during reproduction;
3. Replication: it must be copied because the genetic material is passed during reproduction and division;
4. Variation: it must vary in ways that can account for the known phenotypic differences within each species.
What was known of the genetic material in the 1880s?
- The chromosomes are the carriers of the genetic material.
What was not known of the genetic material in the 1880s?
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Which 3 (groups of) researchers discovered something about the identity of the genetic material?
- Avery, MacLeod and McCarty;
- Hershey and Chase.
Which 2 types of S. Pneumoniae did Griffith study?
- Bacteria that don't secrete a capsule, which have a rough appearance.
Which expected things did Griffith discover during his experiments with mice?
- The mouse survived when R bacteria were injected;
- The mouse survived when R, but heat-killed bacteria were injected.
What did Griffith conclude after his experiment?
What was the aim of the experiment of Avery, MacLeod and McCarty?
How was the experiment of Avery, MacLeod and MacCarty set up?
- To make sure that it weren't some other substances that converted type R into type S, they added DNase (which digests DNA), RNase (digests RNA) and protease (digests proteins).
What were the results of the experiment of Avery, MacLeod and McCarty?
- When DNase was added, no type R was converted into type S.
What did Avery, MacLeod and McCarty conclude after the experiment?
What sort of virus did Hershey and Chase use in their experiment?
How was the experiment of Hershey and Chase set up?
- They gave phages sufficient time to infect bacteria cells.
What were the results of the experiment of Hershey and Chase?
- but most of the S-35 remained outside the cells.
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