L8 pharmocology of weight management and complications of obesity
4 important questions on L8 pharmocology of weight management and complications of obesity
Medical options for weight los --> bariatric surgery
- Effective but not the 'ideal solution'
- only indicated in very obese or patients ar risk
- not to be confused with liposuction
Key messages from Pharma R&D:
- Overweight creates big market
- creativity is unlimited
- no idea is too crazy beforehand
- consider options you thought unthinkable
Second generation CB1 blockers -->
- Different kinetics: relatively lower brain concentrations and more peripheral action
- different dynamics: no inverse agonists like rimonabant, but neutral antagonists or partial agonists
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Physical excursive is beneficial
- Improves symptoms of metabolic syndrome independently from weight loss
- improves cardiometabilic fitness
- improves muscle metabolism
- stimulates immune system
- contributes to weight management
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