Immunology - Lecture Thirty Five : B Cells
3 important questions on Immunology - Lecture Thirty Five : B Cells
What are the 3 functions of antibody in the immune system ?
The 3 functions of antibodies :
These three functions work together to destroy the pathogen
- Neutralisation : binds to microbes and blocks their ability to attach to host cells
- Opsonisation : Label the pathogens for phagocytosis
- Complement activation : They bind to the surface of pathogens to activate complement. This causes MAC formation and cell lysis
These three functions work together to destroy the pathogen
What are memory B-Cells ?
- It is the stimulation of B cells by an antigen and T cell leads to formation of plasma cells and memory cells
- They persist in the lymph tissue
- Express antibodies as BCR's and do not secrete antibodies
- Respond rapidly to antigens and become plasma cells (which produces a specific type of antibody)
What are the differences between the primary and secondary immune response ?
PRIMARY IMMUNE RESPONSE
SECONDARY IMMUNE RESPONSE
- Occurs when we are first exposed to a specific type of antigen
- Takes our body 7-14 days to eliminate the pathogen with relatively low antibody produced
- Mainly IgM
SECONDARY IMMUNE RESPONSE
- Much faster than the primary response
- Takes our body 2-3 days to eliminate the pathogen due to memory cells
- Mainly IgG
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