General - Cytokines - IL-1
3 important questions on General - Cytokines - IL-1
What is the source of IL-1?
Many cell types, including monocytes, macrophages, dendritic cells, NK cells, and non-immune cells such as epithelial and endothelial cells, fibroblasts, adipocytes, astrocytes and some smooth muscle cells.
Which cells does IL-1 have an effect on?
T cells, B cells, monocytes, eosinophils, dendritic cells, fibroblasts, liver cells, vascular endothelial cells and some cells of the nervous system.
What are the effects of IL-1?
Induction of local inflammation and systemic effects such as fever, the acute phase response, and stimulation of neutrophil production
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