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Summary Immunology

Course
- Immunology
- -
- 2018 - 2019
- Vrije Universiteit Amsterdam
- Biomedische Wetenschappen
304 Flashcards & Notes
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A snapshot of the summary - Immunology

  • Lecture 1

  • How do pathogens come into the body? Why via these tissues?
    Via mucosal tissues because these tissues are very permeable.
  • What are examples of mucosal tissues?
    • Respiratory tract
    • Urogenital tract
    • Gastrointestinal tract
  • What are two different classifications of pathogens?
    • Intracellular
    • Extracellular
  • What immune cells belong to the innate immune system?
    • Granulocytes (short life cycle)
    • Macrophage
    • Neutrophils
    • NK cells
    • Complement
  • What is the difference between granulocytes and macrophages?
    Granulocytes kill bacteria and macrophages 'eat' big particles.
  • What does CD mean in CD4 and CD8?
    Cluster of deviation
  • When do you speak of a disturbed immune system?
    • Autoimmune diseases (against 'self')
    • Allergies

    These are both immune responses against harmless things.
  • What is so special about the immune system?
    The immune system is a balance between activation and inactivation (immunity vs tolerance).
  • How can you artificially induce immune responses?
    • Vaccination
    • Anti-tumor therapy
  • What are the three levels of protection?
    1. Barriers: skin, mucous, membranes, chemicals
    2. Innate immune response: immediate response, fast, not specific
    3. Adaptive immune response: slow to be activated, very specific
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