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Summary Infectious Diseases and Vaccine Development

- Infectious Diseases and Vaccine Development
- Harmsen
- 2020 - 2021
- Vrije Universiteit Amsterdam
- Biomedische Wetenschappen
163 Flashcards & Notes
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A snapshot of the summary - Infectious Diseases and Vaccine Development

  • Lecture 1 - Introduction

  • What is meant with the good, the bad and the ugly when talking about microorganisms?
    The good: part of the body, helps the body
    The bad: pathogenic microorganisms, can cause infection
    The ugly: pathogenic, cause severe disease
  • What is meant with the serial interval?
    The time from clinical period in patient 1 to patient 2.
  • What is meant with an endemic disease?
    A certain disease occurs at a baseline level in the population and without new introductions from outside.
  • What is meant with a sporadic disease?
    A disease with a low level and very irregular.
  • What is meant with a cluster?
    A sudden aggregation of cases in time and place ad with common characteristics.
  • What are two types of epidemics?
    Common source (either point source or intermittent) & propagated.
  • What are the lessons learned from the plague?
    • Quarantine
    • Protective clothes
    • Social distancing
    • Isolation of the ill
    • The role of city administrators (they needed to take the measures)
  • What are measures regarding source & transmission?
    • Isolation
    • Treatment
    • Social distancing
  • What are measures regarding contacts?
    • Screening
    • Immunization
    • Chemoprophylaxis
    • Follow up, quarantine
  • Lecture 2 - Basic immunology

  • What did Elias Metchnikffs discover? And what was this the basis for?
    Phagocytic cells, this was the basis for innate immunity.
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