Mechanism and Reactivity - Attack by OH - Hydrolysis of Nitriles
3 important questions on Mechanism and Reactivity - Attack by OH - Hydrolysis of Nitriles
What are the two possible products in the hydrolysis of nitriles?
Amides and carboxylic acids
In the hydrolysis of nitriles what is the reagent of choice when the carboxylic acid is desired?
Aqueous NaOH containing 6-12% H2O2
What are three possible reagents that can be used to obtain the amide product when hydrolyzing nitriles? (treatment with water as work up)
TFA
Acetic acid
Sulfuric acid
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