The role of ATP in metabolism - Phosphorylation of ADP to ATP - Oxidative phosphorylation: the phosphorylation of ADP to ATP linked to the oxidation of metabolic fuels
4 important questions on The role of ATP in metabolism - Phosphorylation of ADP to ATP - Oxidative phosphorylation: the phosphorylation of ADP to ATP linked to the oxidation of metabolic fuels
What is the role of malate? And succinate?
Malate; reduces NAD+ to NADH
Succinate; reduces flavin coenzyme, then ubiquinone (CoQ10, fully oxidized form)
What is a mitochrondrion?
An intracellular organelle with a double membrame structure.
Describe the mitochondrial electron transport chain.
A series of enzymes and coenzymes in the crista membrane. Each reduced by preceding coenzymes and in turn reduced the next until protons and electrons have entered the chain from NADH or reduced flavin.
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In what two ways can the sequence of the electron cariers in the mitochrondrial electron chain be determined?
Concidering elextrochemical redox potential.
Incubating mitochondria with substrates (in absence of oxygen)
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