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Summary Medical Embryology

Course
- Medical Embryology
- 2021 - 2022
- Radboud Universiteit Nijmegen
- Biologie
184 Flashcards & Notes
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A snapshot of the summary - Medical Embryology

  • L2 Developmentl biology

  • Blasocoel spot (animal or vegetal pole) depends on?
    The ootypes of the animal, so where the yolk is located. If yolk more on vegetal pole, blastocoel will most probably be on the animal pole.
  • What cells does the mesoderm consist of ?
    Mesenchyme cells (?)
  • L3 Developmental biology

  • What does define which specialisation a cell will have (or colorcode)?
    The concentration defines the threshold in which the cell will do a certain specialisation
    So the different concentrations of particular morphogens will result in different (end) cells after differentiation. 


    French flag model
  • L4 Developmental biology

  • The five brain vesicles are?
    Telencephalon, Diensephalon, Mesensephalon, Metencephalon, Myelencephalon

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  • eModule notes (Developmental biology)

  • Developmental Hallmarks Drosophila
    • centrolecithal ootype
    • syncytium (cytoplasm with multiple nuclei)
    • syncytial specification (specification of body regions by interactions between cytoplasmic regions before cellularization of the blastoderm) - specific of insects
    • involution and ingression of mesodermal cells
    • after gastrulation specific sets of cells will form imaginal discs giving rise to specific structures after morphogenesis
    • development is 'up-side-down' as nervous system develops ventrally
    Make sure you get familiarized with all these aspects!
  • Why is the Xenopus a great animal model?
    • Embryonic development takes place externally
    • Development is simple and rapid
    • Females produce eggs al year-round
    • Eggs are quite large
    • Entire genome is sequenced
    • Animals are genetically similar to humans
    • Embryos can tolerate extensive manipulation, as they are quite robust
    • Animals are easy to keep in the lab
    • Embryos are easy to grow in a simple culture medium
  • At which pole does cleavage take place?
    The animal pole -> the pole with the least egg yolk (in xenopus)
  • Discoidal cleavage takes place in which animals?
    Birds and fish
  • Holoblastic spiral takes place in which animals
    Annelids, molluscs and flatworms
  • Holoblastic radial takes place in which animals?
    Amphibians (xenopus frog0
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