L11 Human embryology and development
3 important questions on L11 Human embryology and development
Name some neural tube closure defects (NTC):
Spina bifida: no closure of the caudal part (on 27th day)
Anencephalie: no closure of the frontal part (lethal)
Craniorachischisis: no closure over the entire length
Anencephalie: no closure of the frontal part (lethal)
Craniorachischisis: no closure over the entire length
Mesoderm differentiation
In what three regions is the mesoderm divided?
- Somites: 40 pairs of body segments (repeating units, like building blocks) by end week 4
- intermediate mesoderm: just lateral to somites
- Lateral plate: splits to form coelom
Mesoderm derivatives
Name three mesoderm derivatives + subdivisions:
Mesoderm
The coelom in between will become the serous cavities (peritoneal/pericardial/pleural) of the ventral body cavity.
- Praxial mesoderm (somites)
- Sclerotome (skeleton)
- Dermatome
- Myotome (muscles)
- Intermediate mesoderm
- Kidneys and gonads
- Lateral plate mesoderm
- 1. Somatic mesoderm (body walls)
- Dermis of skin
- Bones
- Ligaments
- 2. Splanchnic mesoderm (viscera)
- forms musculature, connective tissue, and serosa of the digestive and respiratory structures
- forms heart and most blood vessels
- 3. Branchial arch mesoderm
- Facial muscles
The coelom in between will become the serous cavities (peritoneal/pericardial/pleural) of the ventral body cavity.
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