Practice exam - Immunology
12 important questions on Practice exam - Immunology
One recognition strategy used by the innate immune system is to detect conserved pathogen associated molecular patterns (PAMP). Which of the following is an example of a well characterised innate immune system receptor ligand pair?
- T-cell receptor and H1N1 influenza A peptide
- TLR4 and lipopolysaccharides (LPS)
- TLR2 and IL-4
- TLR5 and IgG
- T-cell receptor and H1N1 influenza A peptide
- TLR4 and lipopolysaccharides (LPS)
- TLR2 and IL-4
- TLR5 and IgG
Which of the following is a signature cytokine of Th2 like lymphocytes?
- IFN-gamma
- TNF-gamma
- IL-5
- IL-10
- IFN-gamma
- TNF-gamma
- IL-5
- IL-10
Which of the following cytokines induces isotope switching in B cells to the production of IgE antibodies?
- IL-4
- IL-10
- IL-17
- IL-5
- IL-4
- IL-10
- IL-17
- IL-5
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Antigen presenting cells that activate helper T cells must express which one of the following on their surfaces?
- IgE
- Gamma interferon
- Class I MHC antigen
- Class II MHC antigen
- IgE
- Gamma interferon
- Class I MHC antigen
- Class II MHC antigen
Which of the following regarding the high affinity IgE receptor FceRI is true?
- This receptor is expressed on neutrophils when they leave the blood stream
- The receptor is present on basophils in the blood circulation
- The receptor is present on those B cells that produce IgE antibodies
- The receptor expression is induced on mast cells ONLY in the presence of the allergen
- This receptor is expressed on neutrophils when they leave the blood stream
- The receptor is present on basophils in the blood circulation
- The receptor is present on those B cells that produce IgE antibodies
- The receptor expression is induced on mast cells ONLY in the presence of the allergen
All of the following are released by mast cells at degranulation, except:
- Histamine
- Prostaglandins
- IgE antibodies
- Leukotrienes
- Histamine
- Prostaglandins
- IgE antibodies
- Leukotrienes
Eosinophilia in allergic target tissues is associated with:
- Symptoms of an immediate IgE mediated allergy
- Delayed type allergy (type IV)
- Late phase reactions in IgE mediated allergy
- Food allergy in the gut
- Symptoms of an immediate IgE mediated allergy
- Delayed type allergy (type IV)
- Late phase reactions in IgE mediated allergy
- Food allergy in the gut
Which of the following most accurately describes an epidemiologic feature of food allergy?
- Allergy to fish/shellfish is more prevalent among children than among adults.
- Nowadays, allergy to milk and egg seems to be more persistent than in past decades, with fewer children resolving these allergies by age 4 years.
- Food allergy has NOT increased in children over the past three (3) decades.
- Peanut allergy in children never resolves and is always persistent.
- Allergy to fish/shellfish is more prevalent among children than among adults.
- Nowadays, allergy to milk and egg seems to be more persistent than in past decades, with fewer children resolving these allergies by age 4 years.
- Food allergy has NOT increased in children over the past three (3) decades.
- Peanut allergy in children never resolves and is always persistent.
A 27-year old atopic man experienced mild oral allergy syndrome when eating raw apples but tolerates apple juice and baked apple. Which of the following is most likely to be true?
- He has an increased IgE level that binds lipid transfer protein in apple
- He has positive skin test results to commercial extract of apple
- He has an increased IgE levels specific for the Bet v 1 allergen
- The Maillard reaction during heating apple does NOT abrogate IgE binding for this person
- He has an increased IgE level that binds lipid transfer protein in apple
- He has positive skin test results to commercial extract of apple
- He has an increased IgE levels specific for the Bet v 1 allergen
- The Maillard reaction during heating apple does NOT abrogate IgE binding for this person
A child stung by a bee experiences respiratory distress within minutes and lapses into unconsciousness. This reaction is probably mediated by:
- IgE antibody
- IgG antibody
- Sensitized T-cells
- Complement
- IgE antibody
- IgG antibody
- Sensitized T-cells
- Complement
Which of the following methods of controlling exposure to cat allergen is out useful?
- Keep the cat out of the bedroom
- Dispose of the cat.
- Wash the cat once a week.
- Use high-efficiency particle filtration.
- Keep the cat out of the bedroom
- Dispose of the cat.
- Wash the cat once a week.
- Use high-efficiency particle filtration.
A child disturbs a wasp nest, is stung repeatedly, and goes into shock within minutes, manifesting respiratory failure and vascular collapse. This is MOST likely to be due to:
- Systemic anaphylaxis
- Advanced gut leakage
- Coeliac disease reaction
- Toxic reaction
- Systemic anaphylaxis
- Advanced gut leakage
- Coeliac disease reaction
- Toxic reaction
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