Read the summary and the most important questions on NPA clinical exam

• 12 Antimalarials interactions

• What antimalarial is least appropriate if the patient is going to Gambia and is on aripiprazole?

  Mefloquine and aripiprazole have a moderate interaction that increases the risk of irregular heart rhythm

• 13 trastuzumab side effects

• Name 4 side effects of trastuzumab

  Abdominal pain, headache, dry mouth, constipation. *Don't confuse peripheral nephropathy with peripheral neuropathy

• 14 constipation

• 53 yo woman constipated for 2 days. Wants to be comfortable fro dinner party in 3 hours. Give appropriate laxative

  Glycerol suppository

• 15 senna

• How does senna work?

  Stimulates intestinal motility

• 16 warfarin

• What should you do when after drinking alcohol INR is 7 with minor bleeding and target INR is 3.5

  Stop warfarin, give vitamin k and restart warfarin when INR is less than 5

• 18 renal function classification

• What classification of renal function is e GFR of 20ml/min/1.73m^2?

  Severe reduction

• 19 Exemption from payment for a flu vaccine?

• What would make a customer exempt from payment for a flu vaccine?

  Being in the first trimester of pregnancy

• What doesn't exempt someone from payment for a flu vaccine?

  Being 61 years of age, being a secondary carer for a disabled person, being a breastfeeding mother, BMI > 30kg/m^2

• 20 osteoporosis

• What are risk factors for osteoporosis

  Alcohol, cigarette smoking, BMI of 19, early menopause

• What is the best drug regimen for osteoporosis prophylaxis?

  Alendronic acid, calcium carbonate and vitamin D