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Summary Nutrition And The Aging Body

Course
- Nutrition and the Aging Body
- Pol Grootswagers
- 2021 - 2022
- Wageningen University (Wageningen University, Wageningen)
- Nutrition and Health
493 Flashcards & Notes
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A snapshot of the summary - Nutrition and the Aging Body

  • 2 Intro to ageing

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  • What is a healthy lifespan?
    • Healthspan
    • Years of life spend in good health
    • Controversy
    • Helpful concept for interventions preventing aging-related deteriorations


    Healthspan of zero years when having diabetes type 1 from burn onwards

    • Gap with lifespan is increasing
  • What are the main reasons of the gap [gap with lifespan is increasing]
    • Cardiovascular diseases
    • Diabetes mellitus
    • Cancer
    • Alzheimer's disease and dementia


    bodem slides, you want the blue line in stead of the purple line 
  • Where has COVID-19 influence on?
    • Maximum lifespan (possible but not per se)
    • Average lifespan 
    • Healthspan 
    • Socio-economic gap in healthspan 
  • What are the 5 blue zones? And what are blue zones?
    • Loma Linda
    • Nicoya, Costa Rica
    • Sardinia, Italy
    • Icaria, Greece
    • Okinawa, Japan


    1. areas of exceptional longevity
    2. highly active
    3. low level of stress
    4. strong community
    5. locally produced food, non-processed
  • What is the effect of lifestyle on lifespan 
    • smoking 
    • physical inactivity 
    • alcohol abuse 
    • diabetes 
    • BMI
    • hypertension 
    • smoking - 4.8 y
    • physical inactivity - 2.4 y
    • alcohol abuse - 0.5 y
    • diabetes - 3.9 y
    • BMI - 0.7 y
    • hypertension - 1.6 y
  • What includes genetics vs lifestyle?
    • Long-lived sibling increases change to reach high age
    • Parents and offspring of long-lived persons also reach higher ages
    • However, also spouses of long-lived persons reach higher ages


    Longevity families: combination of genetics, environment and cultural factors 
  • Spouses (your men, wife) are not genetically similar, but why do they also have higher change to reach a higher age?
    Because they share 
    • traits
    • behaviour
    • environment
  • What is the estimation of true heredity of lifespan?
    Max 25%
    Most recent estimates around 12%

    Twin studies are used to unravel the true genetics determinants from environmental determinants 

    Compare monozygotic vs dizygotic
  • What are the male aging facts?
    • Testosterone production/ levels decrease gradually beginning around age 30
    • Sperm production does not stop
    • not all men experience low testosterone and sperm production
  • What are the female menopause facts?
    • Estrogen (female sex hormone) production drops rapidly beginning around age 40
    • egg production stops completely
    • all women experience low estrogen and egg production
    • FSH increases!!

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