Try our study magic for free
Summary: Osteorheumatology: A New Discipline?
- This + 400k other summaries
- A unique study and practice tool
- Never study anything twice again
- Get the grades you hope for
- 100% sure, 100% understanding
a PDF, study it super fast
- No sign up, email or credit card needed!
- AI makes unlimited flashcards
- Get unlimited quizzes and tests
- Ask AI anything
- No sign up, email or credit card needed!
- Have and keep perfect overview
- Make flashcards, notes and mind maps
- Review, test and score!
Read the summary and the most important questions on OsteoRheumatology: a new discipline?
-
1 Introduction
This is a preview. There are 2 more flashcards available for chapter 1
Show more cards here -
What is the basic idea underlying OsteoRheumatology?
The importance of the crosstalk between inflammation, cartilage and subchondral bone in disabling conditions like OA and RA. -
2 Bone involvement in OA
This is a preview. There are 1 more flashcards available for chapter 2
Show more cards here -
What is the hallmark of osteoarthritis?
Destruction of cartilage -
What are the keywords in osteoarthritis?
- cartilage
- subchondral bone
- synovial membrane
- low-grade inflammation
- estrogen-deficiency
- wear
- local
-
3 The role of subchondral bone in OA
This is a preview. There are 5 more flashcards available for chapter 3
Show more cards here -
What are the typical skeletal changes in OA?
- increased cortical plate thickness
- flattening and deformation of the articular contour
- bone marrow lesions
- decreased subchondral trabecular bone mass
- tidemark duplication
- osteophyte formation
-
Where is subchondral bone located?
Below the cartilage of the joints and has same properties as the epihyseal plate (growth plate) -
Which two phenotypes can be distinghuised as a result of increased subchondral bone remodeling?
- Sclerosis
- Osteoporosis
-
How is a sclerotic phenotype induced?
By mechanically overloading the subchondral bone on the osteochondral junction. -
How can a subchondral osteoporotic phenotype be induced?
- estrogen deficiency or menopause
- stress shielding
- synovial inflammation
-
What can be said about the quality of the subchondral bone in OA?
The quality is low because the bone is hypomineralized (has probably to do with a collagen type that has low affinity for Calcium). -
What is said about the osteoblast cytokine production?
It has increased production of both bone stimulating and bone degradation signaling cytokines.
- Higher grades + faster learning
- Never study anything twice
- 100% sure, 100% understanding
For my 1st exam I got a C. Then, I started looking for ways to learn better and I came across Study Smart. Since then I have scored a A+, A, A- and another A. I highly recommend it to everyone who wants to hear it. I am so happy with it!!
I was struggling to finish all my first-year subjects for 3 years. Then I discovered Study Smart, which helped me to finish all of them within 3 months.
Because of StudySmart, things are going well in many ways. Before, I always had study stress and no time for anything. Now I feel calm and confident (because of the program). I used to score a B, now I usually score an A or A+.
Hey Chris, I really want to thank you very much for developing the platform, I usually got around C for my exams, now I scored an A+, an A and a A- !!
Since using Study Smart, my average has increased significantly. I even completed a statistics course with a A+ while I'm bad at statistics. I took on extra courses this year, because of Study Smart. Thanks so much!
Ever since I started studying with StudySmart I passed all my exams !!! No more re-sits!! At first, I was happy with a pass and now I only get good grades. Many thanks!
I aced all the courses I studied with Study Smart. For law, I first scored a D, and now an A! I’m 100% sure that I’ll pass all the courses I study with Study Smart.
I always thought I studied well. My grades were fine. I could never have imagined that applying these study skills would have such a huge and direct impact on my grades, my speed and the pleasure I have in learning.
For the first time, I finally feel totally confident about the way I learn. I have the perfect overview and make great progress in terms of speed and the grades I get. Thanks, Chris!
I immediately started to enjoy learning again, and my grades soared. All of a sudden, everything went better. I highly recommend Study Smart to all students..
Being able to create my materials online made the process of studying so much smoother and quicker. I no longer have to spend a huge amount of my time on creating my summaries.
At first, my notes were a mess. Now I use Study Smart to take my notes in a perfectly structured way. It helps me to save a lot of time and do other things I enjoy.
Students that study with Study Smart get better grades. The system applies all the learning methods in such a way that both well-performing students and students who struggle perform much better.
Hi Chris, I would like to thank you very much. Last year I scored C on a course, and this year I got an A+ thanks to your method! Thank you very much!
The largest effect is that my child is more enthusiastic about school! Every parent wants their children to be happy at school, Study Smart made it happen.
In high school, I failed several exams, and that has really changed now. I actually needed this tool very much back then. Since I started studying with StudySmart, I haven't had any D's. My average score is now an A and those are results I would have never had in the past
With my old method, I passed only 3 out of 8 courses. Since I started taking my notes digitally in Study Smart, I have passed all my courses on the first try. For me, StudySmart takes away the stress of wondering if I will pass or not.
Thanks to StudySmart, I passed all my exams, and with better grades than before! On top of that, I have mastered a very good study method now, which I am confident will help me earn my degree.
