Food drug interactions
11 important questions on Food drug interactions
What happens with the case where a man started to drink cranberry juice?
Drug on a full stomach or empty stomach?
This can also depend on the form of the drug. Capsules can be longer in the stomach than a tablet for example.
What is the Biopharmaceutics classification system (BCS)? [FDA]
When a drug is high soluable and high permeable, that is a good drug without much side effects, like paracetamol.
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What is the effect of high fat meal on the BCS?
Class 2: the bioavailability will be higher and time of absorption is depending.
Class 3: will have a lower bioavailability and a longer absorption time.
Class 4: this is all really dependent and different. These are the new drugs who are a bit difficult and more complex.
What is brick dust?
What are examples of food interaction with CYP450?
What drugs are more interacting with grapefruit?
Why should you not change from diet when on a lot of drugs?
Why do all drugs react different, also when in the same therapeutic classes.
What is Saquinavir and indinavir?
Indinavir: precipitates in stomach due to higher pH after meal rich in proteins or fat.
What can be reasons for mallnutrition caused by drugs?
Taste and smell
Appetite and satiation (+ or -)
GI physiology (diarhoea)
General metabolism
Micronutrient absorption and metabolism
Microbiota
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