Summary: Reader Microbial Disease Mechanisms

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  • 2 Structure and functio of bacterial cells

  • 2.2 Appendages: flagella, fimbriae and pili

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  • 3 ways to spot bacterial movement

    1. Staining technique
    2. Swim medium
    3. Direct observation in wet mount
  • F pillus / Sex pilus

    Stabilize mating during conjugation
  • 2.3 The cell envelope: capsules, cell walls and S-layers

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  • Gramnegative Cell wall

    - Turns pink by staining
    - Single peptidoglycan  layer with outer membrane
    - LPS as unique component
  • Penicillin & beta-lactam antibiotics action

    Block transpeptidase and carboxypeptidase enzymes during the assembly of the murein cell wall
  • Lipoteichoic acid (LTA)

    The teichoic acids that are anchored into the plasma membrane
  • Omp C and F

    Porins that allow hydrophillic solubles to cross the membrane
  • 2.5 The plasma membrane

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  • Plasma membrane (function)

    Selective permeability barrier
  • Fluid mosaic model

    The arrangement of proteins and lipids to form a membrane
  • Ion driven transport system (IDT)

    Used for accumulation of many ions and amino acids
  • Binding-protein dependent transport system (BPDT)

    Used for sugars and amino-acids

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