Bacterial Toxins - Bacterial endotoxin - Endotoxic shock
3 important questions on Bacterial Toxins - Bacterial endotoxin - Endotoxic shock
What 3 events are triggered in monocytes and macrophages when interact with LPS?
1. Cytokine production
2. Complement cascade activation
3. Coagulation cascade activation
2. Complement cascade activation
3. Coagulation cascade activation
2. Activation of the complement cascade
C3a and C5a cause histamine release and affect neutrophil chemotaxis and accumulation --> results in inflammation
3. Activation of the coagulation cascade composes (4)
A. Coagulation
B. Alterative complement activation
C. Plasmin actication
D. Kinin activation
B. Alterative complement activation
C. Plasmin actication
D. Kinin activation
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