Influence on disease
3 important questions on Influence on disease
What is the influence of stress --> immune suppression --> disease?
Acute stress --> disregulation tissue damage --> organic disease
with an acute stress the defense is temporary increased
acute response --> not good when very frequent
with an acute stress the defense is temporary increased
acute response --> not good when very frequent
Chronic stress & immune-related disease
- social isolation/ loneliness
- interpersonal stressors ('relationship-stress')
- loss partner/ child
- long-term care giving for chronic patient
- depression/ hopelessness
-->
more immune suppression
more immune-related disease outcomes
- interpersonal stressors ('relationship-stress')
- loss partner/ child
- long-term care giving for chronic patient
- depression/ hopelessness
-->
more immune suppression
more immune-related disease outcomes
Examples of immune related disease outcomes:
- Infectious diseases - e.g. cold, flue, herpes, Epstein Barr virus (‘Pfeiffer’), AIDS… (even ‘dose-response’-relationships with stress!)
- Cancer --- partly via immunosuppression...
- AIDS: HIV atacks immune cells (T-helper cells)
- Wound healing
- Cancer --- partly via immunosuppression...
- AIDS: HIV atacks immune cells (T-helper cells)
- Wound healing
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