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Summary The developing brain

Course
- The developing brain
- hylke
- 2015 - 2016
- Vrije Universiteit Amsterdam
- Bewegingswetenschappen
258 Flashcards & Notes
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A snapshot of the summary - The developing brain

  • Embryonic brain development

  • Which structures form out of the endoderm?
    urinary, digestive and respiratory systems
  • Which structure comes from the notochord?
    vertebral column
  • Which structure comes from the neural tube?
    CNS
  • How is dorsoventral specification achieved?
    A network of inductive signals specify the neuron types via specific combination of transcription factors
  • What are homeotic genes?
    Similar genes(HOX genes), are transcription factors that specify segment identity to create anteroposterior specification
  • What is hensens node?
    A knot which moves anterior to posterior relasing more Retinoic acid as it grows, regulating the colinear expression of HOX genes.
  • What are the two zones where neuro genesis takes place?
    Ventricular zone and the sub ventricular zone
  • What neurons are generated in the ventricular zone?
    It are neuroepithelial stem cells which generate projection neurons and are only active during development
  • What neurons are generated in the subventricular zone?
    The germinal zone generates interneurons that migrate to the olfactory bulb and the into the hippocampus and are active throughout life.
  • How does radial migration work?
    Cells go up from the ventricular zone to the cortical plate through the previous layer
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